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| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.contributor.author | Avendaño, Maria Eugenia | - |
| dc.contributor.author | Poletto, Adriana | - |
| dc.contributor.author | Bonanno, Marina Soledad | - |
| dc.contributor.author | Davison, Mario Ricardo | - |
| dc.contributor.author | Zeni, Susana Noemi | - |
| dc.date.accessioned | 2023-05-03T16:34:08Z | - |
| dc.date.available | 2023-05-03T16:34:08Z | - |
| dc.date.issued | 2020-11 | - |
| dc.identifier.uri | http://rid.unrn.edu.ar/handle/20.500.12049/10100 | - |
| dc.language.iso | en | es_ES |
| dc.relation.uri | https://www.medicinabuenosaires.com/ | es_ES |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | - |
| dc.title | Assessment of jawbone microarchitecture in bisphosphonate- treated sheep by cone-beam computed tomography | es_ES |
| dc.type | Objeto de conferencia | es_ES |
| dc.rights.license | Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) | - |
| dc.description.filiation | Avendaño, Maria Eugenia. Universidad Nacional de Cuyo | es_ES |
| dc.description.filiation | Poletto, Adriana. Facultad de Odontología.Universidad Nacional de Cuyo | es_ES |
| dc.description.filiation | Bonanno, Marina Soledad. INIGEM.UBA.CONICET | es_ES |
| dc.description.filiation | Davison, Mario Ricardo. Universidad Nacional de Rio Negro. Río Negro; Argentina. | es_ES |
| dc.description.filiation | Zeni, Susana Noemi. UBA/CONICET. | es_ES |
| dc.subject.keyword | Tomografía | es_ES |
| dc.subject.keyword | Hueso | es_ES |
| dc.subject.keyword | PTH | es_ES |
| dc.subject.keyword | Bifosfonatos | es_ES |
| dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
| dc.subject.materia | Ciencias Médicas y de la Salud | es_ES |
| dc.origin.lugarDesarrollo | Universidad Nacional de Río Negro | es_ES |
| dc.description.resumen | The cone-beam computed tomography (CBCT) is a non-invasive 3D reconstruction technique that enables to assess jawbone micro-architecture. It is used to illustrate results through 3D images. In the present report, the combination of CBCT with other techniques was used to evaluate changes in composition and micro-architectural structure quantity of the ewe jawbone after oestrogen withdrawal (OVX) and/or chronic treatment with high doses of zoledronic acid (zol). Three groups of adult Corriedale ewes, 35 to 40 kg body weight were used: OVX: OVX ewes receiving saline solution; ZOL: OVX ewes treated with Zol (4 mg/month) for 28 months for high cumulative dose of ZOL in bones and SHAM: SHAM ewes receiving saline solution (control). At the end of the study, hemi-mandibles were extracted: Bone mineral density (BMD) and content (BMC) of the mandibles were evaluated ex vivo by DXA (Lunar DPX); CBCT was performed using Planmeca Promax 3D Classic. Results of CBCT: OVX as compared to SHAM ewes significantly decreased BMC and BMD (p<0.001); BV/ TV (%), Tb. Th, connectivity and anisotropy (p<0.0075; p<0.0075, p<0.001 and p<0.02, respectively) while Tb. Sp (p<0.0002) was significantly increased. Zol treatment did not show statistical differences when compared to SHAM group. Zol showed values of anisotropy significantly higher than OVX group (p<0.018) and Tb.Sp significantly lower than OVX groups (p<0.043). BV/ TV (%), Tb. Th and connectivity as compared to OVX group showed a clear tendency to be higher and almost reached significance (p=0.055; p=0.061 and p=0.054, respectively. Maxillary BMC and BMD were lowest in OVX ewes (p<0.05) and were significantly higher in ZOL than in SHAM ewes (p<0.05). Conclusion: The CBCT technique was useful to evaluate the deterioration of the bone quality by estrogen withdrawal and the recovery by ZOL treatment. | es_ES |
| dc.relation.journalTitle | REUNIÓN DE SOCIEDADES DE BIOCIENCIAS 2020 / LXV REUNIÓN ANUAL DE LA SOCIEDAD ARGENTINA DE INVESTIGACIÓN CLÍNICA (SAIC) / LXVIII REUNIÓN ANUAL DE LA SOCIEDAD ARGENTINA DE INMUNOLOGÍA (SAI) / REUNIÓN ANUAL DE LA SOCIEDAD ARGENTINA DE FISIOLOGÍA (SAFIS) | es_ES |
| dc.type.subtype | Resumen | es_ES |
| Aparece en las colecciones: | Objetos de conferencia | |
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| Archivo | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| Revista medicina 2020-62.pdf | 193,52 kB | Adobe PDF | Visualizar/Abrir |
Este documento es resultado del financiamiento otorgado por el Estado Nacional, por lo tanto queda sujeto al cumplimiento de la Ley N° 26.899
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